While not every case requires it, genetic testing before In Vitro Fertilization (IVF) can help fertility specialists select the healthiest embryos and improve success rates. This is especially useful for couples who are facing complex fertility issues.
At Bangkok Central Clinic, advanced Preimplantation Genetic Testing (PGT) services for IVF help screen for chromosomal abnormalities and prevent the transmission of genetic disorders, promoting a safe and successful pregnancy. Some may wonder about the difference between PGT vs PGD, or Preimplantation Genetic Diagnosis, which is the older term for PGT.
What Is PGT Testing in IVF?
PGT is a modern diagnostic technique performed during the IVF process to evaluate embryos before they’re transferred into the uterus. It helps detect chromosomal or congenital abnormalities early, ensuring that only healthy embryos are selected for transfer. This improves implantation rates and reduces the risk of miscarriage.
PGT is an important step in reproductive medicine, particularly for couples with infertility challenges, advanced maternal age, or a history of genetic disorders. Identifying chromosomally normal embryos helps more couples have successful IVF outcomes.
Different Types of PGT Testing in IVF
A PGT test is chosen based on the patient’s medical background, family history, and fertility goals. Each PGT type addresses reproductive or genetic concerns, such as:
PGT-A (Preimplantation Genetic Testing for Aneuploidy)
- Detects embryos with abnormal chromosome numbers, known as aneuploidy.
- A healthy embryo has 46 chromosomes (23 pairs), while an aneuploid embryo has too many or too few, which can lead to miscarriage, implantation failure, or a baby with a genetic condition like Down Syndrome.
- Recommended for women aged 30 or older, those with recurrent miscarriages, or failed IVF cycles.
PGT-M (Preimplantation Genetic Testing for Monogenic Diseases)
- Screens for single-gene disorders inherited from one or both parents, such as thalassemia, cystic fibrosis, and Huntington’s Disease.
- Ideal for couples with a known family history of genetic conditions or hereditary diseases.
PGT-SR (Preimplantation Genetic Testing for Structural Rearrangements)
- Detects chromosomal translocation or structural rearrangements in embryos that could cause implantation failure or miscarriage.
- Recommended for couples who’ve experienced multiple IVF failures or early pregnancy losses.
When is PGT Testing Recommended for IVF?
Genetic testing before IVF provides valuable insight into embryo quality. While genetic testing isn’t a must for every IVF case, it’s highly beneficial in specific situations for:
- Couples with a history of miscarriage or recurrent pregnancy loss
- Women of advanced maternal age of 35 and over
- Couples with a family history of inherited genetic disorders
- Patients with multiple failed implantation attempts
- Individuals using donor sperm or eggs who want chromosomal assurance
- Patients planning fertility preservation through egg freezing
Benefits of PGT Testing for IVF Couples
PGT testing offers several advantages for those undergoing IVF, including:
Improved IVF success rates: By selecting embryos with the correct number of chromosomes, implantation and pregnancy rates increase significantly.
Reduced risk of miscarriage: Detecting chromosomal errors early lowers the chances of early pregnancy loss.
Healthier pregnancy outcomes: Ensures embryos have normal genetic makeup, contributing to safer pregnancies and healthier babies.
Informed decision-making: Fertility doctors can recommend the most effective and personalized treatment paths, allowing couples to make confident choices.
Peace of mind: Knowing the embryos have been genetically screened helps reduce stress and anxiety during the IVF process.
Does PGT Guarantee IVF Success?
While PGT significantly improves the likelihood of success, it’s important to have realistic expectations. PGT cannot guarantee pregnancy, but it increases the chances of a healthy implantation. Discussing the test results with a fertility specialist is essential before making embryo transfer decisions.
Genetic Testing Before IVF at Bangkok Central Clinic
Bangkok Central Clinic combines advanced IVF technology with personalized care to support each couple throughout their fertility journey. Led by board-certified reproductive medicine specialists with extensive hands-on experience, we utilize state-of-the-art laboratory equipment for accurate and reliable genetic analysis.
Every couple received a comprehensive consultation and fertility evaluation before deciding on PGT testing and personalized fertility treatment plans based on each patient’s medical condition and goals. Our doctors personally guide each patient at every stage of their treatment to ensure safety and optimal results.
Schedule your consultations to learn more about genetic testing for IVF and which PGT is right for your needs.
References:
- Is PGT the Future of IVF? When to Consider Preimplantation Genetic Testing. Retrieved on 4 November 2025 from https://www.rmia.com/fertility-treatments/is-pgt-the-future-of-ivf-when-to-consider-preimplantation-genetic-testing/
- Why the Preimplantation Genetic Diagnosis is Necessary with Donor Egg IVF? Retrieved on 4 November 2025 from https://ovobank.com/why-the-preimplantation-genetic-diagnosis-is-necessary-with-donor-egg-ivf/
